Eminem, left, and Jay-Z tag-team the crowd at Detroit's Comerica Park.

*Thursday night marked the beginning of the four-date Home And Home tour featuring Eminem and Jay-Z performing in their respective hometowns of Detroit and New York.

Eminem’s Comerica Park was up first, with the rapper turning in “an exhaustive, guest-filled 100-minute performance that spanned his entire recording career with full or partial performances of 33 songs.

Some 42,000 fans screamed as Slim Shady took the stage yelling, “Goddamn it, Detroit, I’m back, man. Did you miss me, or what?”

In addition to hype man Denuan Porter — the D12 mate who’s replaced Eminem’s late mentor Proof — at his side, there was DJ Alchemist and a full band that featured “Lose Yourself” and Was (Not Was) alumnus Luis Resto on keyboards, as well as an extensive stack of pre-recorded vocal layers. Detroit rapper Trick Trick came out for some hometown love with “Welcome 2 Detroit,” while the rest of D12 came out for “Fight Music,” “Purple Pills” and the comical “My Band.”

B.o.B., who opened the evening with his own half-hour set, recreated “Airplanes Pt. II,” though Eminem band singer Liz Rodrigues subbed for Paramore’s Hayley Williams – as she also did for Rihanna on “Love the Way You Lie” and Dido on “Stan.”

Drake showed up for a version of his hit, “Forever,” proclaiming it an “honor” to perform with “the legend that is Eminem.” 50 Cent joined Eminem for “Patiently Waiting,” then gave the star a break while he performed “I Get Money” and “In Da Club” with G-Unit cohort Lloyd Banks.

Dr. Dre came on stage for “Still Dre” and “Nuthin’ But a ‘G’ Thang,” with Eminem taking up Snoop Dogg’s parts. When Eminem led the crowd in chanting for Dre’s long-awaited “Detox” album, the producer – who sported a Proof T-shirt – promised, “I’m comin’!”

Jay-Z opened the show 30 minutes earlier, pausing for a moment after taking the stage and telling the show’s directors to turn up the house lights so he could soak up the moment.

“This is hip-hop music,” he said, “and this is how far we’ve come.”

His two shows at Yankee Stadium are scheduled for Sept. 13 and 14.

According to USA Today:

Jay-z began his set to a blast of lights and squalling rock, alone at center stage to rap the intro from album “The Dynasty.” From there it was a fast-paced and at times poignant set of hits and medleys that led to a closing climax of “Empire State of Mind” and “Numb.”

Backed by a tight live band, Jay welcomed guests Young Jeezy and Memphis Bleek and paid tribute to fallen stars, including Detroit’s Proof and Aaliyah.