*Mark your calendar. The last episode of “The Oprah Winfrey Show” will air May 25, her Chicago-based Harpo Productions has announced.

In November 2009, Winfrey revealed live on her show that she would end her run after the 25th season. She since has launched cable’s Oprah Winfrey Network.

“The Oprah Winfrey Show” has been in reruns for the last few weeks. But Winfrey tweeted Thursday that she was “hard at work planning the final shows” and new episodes would begin April 7.

The final episode brings an end to what has been television’s top-rated talk show for more than two decades. It airs in 145 countries worldwide.