*”Prison Break” star Wentworth Miller will appear as a guest-star on Fox’s “House,” TVLine reports.

The actor will play a patient of the week after Dr. House (Hugh Laurie) gets released from jail. “He plays a real altruist,” creator David Shore tells the site. “And there’s some question as to whether that’s his symptom or not.”

The appearance will mark Miller’s first TV appearance since a 2009 episode of “Law & Order: Special Victims Unit.”

House returns Monday, Oct. 3 at 9/8c on Fox. Miller’s episode will air later that month.